Bristol-Myers Squibb’s Opdivo is being recommended by NICE to treat a certain form of lung cancer on the NHS in England, via the Cancer Drugs Fund. The cost watchdog has issued a Final Appraisal Determination (FAD) recommending that the drug’s use to treat both squamous and non-squamous forms of non-small cell lung cancer (NSCLC), after
Actelion says it is disappointed by the decision made by Scottish cost regulators to refuse NHS funding for pulmonary arterial hypertension drug Uptravi. The Scottish Medicines Consortium (SMC) issued guidance not recommending use of Uptravi (selexipag) for a sub-population of adult patients with the potentially life-threatening condition, which leads to an increase in blood pressure
Novartis has entered a clinical research collaboration with Bristol-Myers Squibb to investigate the safety, tolerability, and efficacy of Mekinist in combination with Opdivo and Opdivo + Yervoy regimen. The cancer treatments are being used as a potential option for metastatic colorectal cancer in patients with microsatellite stable tumours where the tumours are proficient in mismatch
Bristol-Myers Squibb have announced that they will be acquiring Flexus Biosciences in an agreement worth up to $1.25 billion. Flexus are a biotechnology company which specialises in the discovery, development, and commercialisation of small-molecule cancer immunotherapies targeting regulatory T cells. The acquisition will involve an $800 million upfront payment, giving Bristol-Myers Squibb full rights to
Bristol-Myers Squibb have announced positive third quarter results for 2014, beating earlier forecasts after stronger-than-expected revenues for the period. The biopharmaceutical company posted earnings on Friday of $721 million, or $0.43 a share, an increase from earnings of $692 million, or $0.42 per share, in Q3 of 2013. Once adjusted for special items, Bristol-Myers Squibb’s
Results of a clinical trial combining Bristol-Myers Squibb’s Yervoy and Nivolumab show an exceptional improvement in tumour regression and overall survival rate for patients with advanced melanoma. Mario Sznol of Yale University School of Medicine, reporting the results of the early-stage study, commented that “this is the first trial conducted with this combination in melanoma.”
Bristol-Myers Squibb (B-MS) yesterday announced a worldwide research partnership and license agreement with CytomX. The collaboration plans to discover, develop and commercialise novel therapies against multiple immuno-oncology targets using CytomX’s proprietary Probody Platform. Probodies are monoclonal antibodies selectively activated within the cancer microenvironment, to focus the activity of therapeutic antibodies to tumours and helping spare
